CARBONYL REDUCTION OF FLUBENDAZOLE IN THE HUMAN LIVER: STRICT STEREOSPECIFICITY, SEX DIFFERENCE, LOW RISK OF DRUG INTERACTIONS

Carbonyl Reduction of Flubendazole in the Human Liver: Strict Stereospecificity, Sex Difference, Low Risk of Drug Interactions

Flubendazole (FLU), an anthelmintic drug of benzimidazole type, is now considered a promising anti-cancer agent due to its tubulin binding ability and low system toxicity.The present study was aimed at determining more information about FLU reduction in human liver, because this information has been insufficient until now.Subcellular fractions from

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Real world evidence: An Indian perspective

Randomized controlled trials (RCTs) are the gold standard for measuring the safety and efficacy of drugs.However, they cerimonia are being challenged by payers and health care providers since they are looking for real world evidence (RWE) to validate whether the new intervention provides similar safety and efficacy as reported in RCT data.RWE uses

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Effect of the FIFA 11+ soccer specific warm up programme on the incidence of injuries: A cluster-randomised controlled trial.

BackgroundSoccer players incur injuries that typically affect their performance.Injuries are caused by intrinsic and extrinsic Terminal Release Set factors that call for multifactorial preventive interventions.The study examines the impact of the FIFA 11+ warm up programme on the incidence and severity of injuries in second division soccer players

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Attentional Biases toward Attractive Alternatives and Rivals: Mechanisms Involved in Relationship Maintenance among Chinese Women.

A long-term romantic relationship can offer many benefits to committed individuals.Thus, humans possess relationship maintenance mechanisms to protect against threats from those who serve as attractive alternatives or intrasexual rivals.Many studies have indicated that romantic love can act as a commitment device to activate these mechanisms.To exa

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